Design, Synthesis, Drug-Likeness and In Silico Prediction of Polycyclic Aromatic Schiff base Tethered Organosilatranes

The present article includes the generation of aromatic Schiff base tethered organosilatranes via two step synthetic pathways starting from anthracene-10-carbaldehyde and 1H-indole-3-carbaldehyde. synthesis was achieved by employing condensation reaction followed transesterification methodology. prepared containing schiff based ligands were structurally authenticated using spectroscopic techniques such as FT-IR, NMR mass analysis. compounds also scrutinized for in silico physiochemical properties Molininspiration ADMET software results revealed their good biological potential drug discovery.